Posts Tagged ‘Allergy Testing’

High Street allergy tests mislead public

Monday, February 22nd, 2010

The Sunday Times newspaper has again produced a masterpiece of investigative journalism (Sunday 21st February 2010) highlighting the frightening number of nonsense allergy and food intolerance tests available in central London. It is amazing that there is no public watchdog to prevent these unvalidated and unscientific allergy tests from being promoted to unsuspecting members of the public by inadequately trained practitioners and nutritionalists. Well done to Gillian Passmore and the Sunday Times for again drawing attention to the issue of misleading unorthodox allergy testing.

http://www.timesonline.co.uk/tol/life_and_style/health/article7034867.ece

Irritable bowel syndrome (IBS)

Thursday, January 14th, 2010

Irritable bowel syndrome otherwise called IBS is a common medical condition affecting the lower bowel in 1 in 5 young adults. Females are especially prone to IBS which presents with one or more of 3 cardinal symptoms:

A. Abdominal pain and spasm which eases when emptying the bowels.

B. Bloating, fullness on eating and abdominal distension with wind.

C. Change in bowel habit with passage of frequent loose mucus-laden stools (an enhanced gastro colic reflex), often alternating with episodes of constipation.

Other more serious bowel conditions such as food allergies, inflammatory colitis, stomach ulcers, intestinal infection and coeliac disease may cause similar but more intense symptoms, and will need to be excluded by testing. A few simple blood tests undertaken by your GP (such as ESR, CRP, FBC) will exclude colitis or gut infection, while specific IgE allergy testing will identify food allergy and coeliac screening measuring Tissue Transglutaminase antibodies will exclude gluten intolerance. Certain non-specific food intolerances may be triggers for IBS and these include excess fruit intake, wheat, dairy produce, onions, excess tea, coffee, alcohol and highly insoluble dietary fibre such as bran, all of which may exacerbate IBS symptoms. The artificial sweetener Sorbitol and processed starch in ready meals may also promote IBS. While emotional stress, masked depression and missed or erratic meals may also be triggers, whereas taking a regular Probiotic supplement (Acidophilus GG) and drinking plenty of filtered water every day may calm the symptoms.

Discuss any concerns you might have regarding food allergies, intolerance or colitis with your GP, Practice Nurse or a qualified Dietician.

http://www.nice.org.uk/guidance/index.jsp?action=byID&o=11927

18% increase in food allergies amongst US children

Wednesday, November 18th, 2009

A scientific study due to be published in the American medical journal Pediatics (December 2009) has found a massive 18% increase in reported food allergies amongst US children (under 18 yrs of age).  This increased reporting of food allergies took place over the last decade between 1997 and 2007.  While between 1993 and 2006 ambulatory visits to the doctor for food allergies have tripled.  In 2007 alone, 3.9% of US children reported food allergic conditions.  The most severely affected were ethnic minorities such as Hispanics. In 2005 to 2006, an estimated 9% of US children had detectable peanut IgE in their blood on allergy testing while over the same period hospitalisations with a diagnosis of food allergy also tripled. It is uncertain whether this trend is due to a true increase in food allergic diseases or represents increasing allergy testing and physician and parental food allergy awareness.

http://pediatrics.aappublications.org/cgi/content/abstract/peds.2009-1210v1

Home hygiene, infections and allergies

Thursday, November 12th, 2009

A recent study on children attending day care or nurseries by de Jongste in the American Thoracic Society journal cast some doubt on the so-called Hygiene Hypothesis for allergy development. The Hygiene Hypothesis notion that farm animal faeces exposure and childhood infections will prevent allergies has been promoted for decades.  The hygiene hypothesis essentially links a more clean and sterile home environment with the overall rise in allergies seen in many developed Western counties.  Poor living conditions with early exposure to germs, infections and parasites seem to shift the infant’s immune system into survival mode (TH1) and away from allergy mode (TH2) when allergy testing. However this immune switching probably occurs very early in the first few months of life. Therefore as mentioned in the American study, day care centre exposure and subsequent childhood infections may have little impact on allergy development. Particularly if the child attends a day-centre after one year of age when their immune type  reactivity is more established.  It still seems likely that a germ-filled household with difficult living conditions and plenty of sickly older siblings will be more protective from allergies while a sterile, insular environment in early infancy seems to promote allergies.

http://news.bbc.co.uk/2/hi/health/8241774.stm

IgG antibody tests don’t indicate food intolerances.

Thursday, October 29th, 2009

In the UK, blood tests for immunoglobulin G4 (IgG4) against foods are actively promoted for the diagnosis of food intolerance and hypersensitivity. Mounting clinical research indicates that food-specific IgG4 allergy testing does not indicate (imminent) food allergy or intolerance, but is rather a normal physiological response by the immune system after food exposure. In fact IgG4 is more likely to indicate food tolerance and that the person can safely eat that food with no adverse effect. This should not be confused with IgE which is the main allergy antibody used in allergy testing and this has an established “track record” in conventional allergy diagnosis.

Not really convinced? Have a look at these research papers:

No recommendation for IgG and IgG4 testing against foods  
J. Kleine-Tebbe, I. Reese, B. K. Ballmer-Weber, K. Beyer, S. Erdmann, Th. Fuchs, M. Henzgen, A. Heratizadeh, I. Hutt egger, L. Jäger, U. Jappe, U. Lepp, B. Niggemann, et al Allergo J 2009;4: 267

Testing for IgG4 against foods is not recommended as a diagnostic tool: EAACI Task Force Report*  
 Stapel SO, Asero R, Ballmer-Weber BK, Knol EF, Strobel S, Vieths S, Kleine-Tebbe J.
 Allergy 2008 July;63(7):793-796.

Unproven techniques in allergy diagnosis.  
 Wuthrich B.
 J Investig Allergol Clin Immunol 2005;15(2):2-90

Peanuts allergy cure is here!

Saturday, October 17th, 2009

In a recent peanut allergy study at Addenbrookes Hospital in Cambridge, traces of peanut flour were used to desensitise 18 highly peanut allergic children. At the end of the study conducted in a controlled hospital environment, they were able to consume 12 peanuts each without any allergic reaction. The study involved eating minute trace amounts of peanut flour mixed with food or drinks on a daily basis to slowly induce peanut tolerance.  Then at regular 2 weekly intervals the peanut flour dose was doubled so that by the 10th hospital visit, they each ate 5-6 peanuts each without reacting on allergy testing. But to maintain thispeanut tolerance they will have to continue eating peanuts regularly on a daily basis, otherwise they may lose this tolerance and their peanut allergy recur.

WARNING: This was a highly controlled study in hospital and peanut allergic children should not be given peanut flour unsupervised!

http://news.bbc.co.uk/2/hi/health/7899383.stm

Should Allergy Testing be done in Pharmacies?

Saturday, October 17th, 2009

The British Society for Allergy and Clinical Immunology (BSACI) has recently raised concerns about allergy testing in pharmacies.

They site a major problem being that pharmacy training involves education about medicines, not about clinical disease, patient history taking, psychology etc. This means that pharmacists do not know what the possibilities for diagnosis are in patients who present with, say, a blocked nose. (more…)