Studies show that systematically eradicating the Staph from the skin will make the eczema easier to control and ultimately clear. In an established infection, the eczema will spread rapidly appearing bright red, crusty, weepy and blistered. The Staph can also persist by being harboured in the nasal passages, under dirty finger nails and in moist skin creases. Fortunately most Staph will be eliminated by antibiotic skin creams such as Mupirocin (Naseptin) or Fusidic acid (Fucidin) as well as by antiseptic skin disinfectants such as povidine iodine (Betadine), hydrogen peroxide, potassium permanganate and chlorhexidine (Hibitane). The beneficial effect of using sodium hypochlorite (found in bleech) and silver impregnated garments has not been proven.  In more extensive Staph infections presenting with Impetigo (skin honey crusts), Folliculitis (pimples and pustules) and Cellulitis (widespread skin surface infection), oral antibiotics such as Flucloxacillin, Erythromycin and Co-amoxyclav will effectively treat the skin infection (unless the superbug MRSA (Methicillin Resistant Staphylococcus Aureus) is present).

http://pediatrics.aappublications.org/cgi/content/abstract/120/Supplement_3/S122