Posts Tagged ‘Food Intolerances’

NICE Food Allergy Guidelines in Children

Thursday, August 12th, 2010

The National Institute for Health and Clinical Excellence (NICE) has released consultation guidelines for diagnosing and treating food allergy in children and young people.  Although long overdue these guidelines are most welcome. This document released this month highlights that in Europe and North America 6 – 8% of children under 3 years suffer with some form of IgE mediated food allergy.  While only 25-40% of children with a self diagnosed food allergy will actually have a food allergy confirmed. The incidence of non-IgE food allergies is largely unknown due to the limited accurate diagnostic tests available. The guidelines stress that the clinical history of the food allergy taken by a competent practitioner is most important in diagnosing an allergy and allergy tests done in isolation can be misleading. Skin Prick tests and specific IgE testing on a blood sample are the most reliable food allergy tests available. Diagnosing food allergies and intolerances using Vega testing, applied kinesiology, hair analysis, leucocytotoxic testing and IgG blood tests are inaccurate and should be discouraged.

 Reference:  Food allergy in children and young people: Guideline consultation www.nice.org.uk

http://www.bbc.co.uk/news/health-10925371

Irritable bowel syndrome (IBS)

Thursday, January 14th, 2010

Irritable bowel syndrome otherwise called IBS is a common medical condition affecting the lower bowel in 1 in 5 young adults. Females are especially prone to IBS which presents with one or more of 3 cardinal symptoms:

A. Abdominal pain and spasm which eases when emptying the bowels.

B. Bloating, fullness on eating and abdominal distension with wind.

C. Change in bowel habit with passage of frequent loose mucus-laden stools (an enhanced gastro colic reflex), often alternating with episodes of constipation.

Other more serious bowel conditions such as food allergies, inflammatory colitis, stomach ulcers, intestinal infection and coeliac disease may cause similar but more intense symptoms, and will need to be excluded by testing. A few simple blood tests undertaken by your GP (such as ESR, CRP, FBC) will exclude colitis or gut infection, while specific IgE allergy testing will identify food allergy and coeliac screening measuring Tissue Transglutaminase antibodies will exclude gluten intolerance. Certain non-specific food intolerances may be triggers for IBS and these include excess fruit intake, wheat, dairy produce, onions, excess tea, coffee, alcohol and highly insoluble dietary fibre such as bran, all of which may exacerbate IBS symptoms. The artificial sweetener Sorbitol and processed starch in ready meals may also promote IBS. While emotional stress, masked depression and missed or erratic meals may also be triggers, whereas taking a regular Probiotic supplement (Acidophilus GG) and drinking plenty of filtered water every day may calm the symptoms.

Discuss any concerns you might have regarding food allergies, intolerance or colitis with your GP, Practice Nurse or a qualified Dietician.

http://www.nice.org.uk/guidance/index.jsp?action=byID&o=11927

IgG antibody tests don’t indicate food intolerances.

Thursday, October 29th, 2009

In the UK, blood tests for immunoglobulin G4 (IgG4) against foods are actively promoted for the diagnosis of food intolerance and hypersensitivity. Mounting clinical research indicates that food-specific IgG4 allergy testing does not indicate (imminent) food allergy or intolerance, but is rather a normal physiological response by the immune system after food exposure. In fact IgG4 is more likely to indicate food tolerance and that the person can safely eat that food with no adverse effect. This should not be confused with IgE which is the main allergy antibody used in allergy testing and this has an established “track record” in conventional allergy diagnosis.

Not really convinced? Have a look at these research papers:

No recommendation for IgG and IgG4 testing against foods  
J. Kleine-Tebbe, I. Reese, B. K. Ballmer-Weber, K. Beyer, S. Erdmann, Th. Fuchs, M. Henzgen, A. Heratizadeh, I. Hutt egger, L. Jäger, U. Jappe, U. Lepp, B. Niggemann, et al Allergo J 2009;4: 267

Testing for IgG4 against foods is not recommended as a diagnostic tool: EAACI Task Force Report*  
 Stapel SO, Asero R, Ballmer-Weber BK, Knol EF, Strobel S, Vieths S, Kleine-Tebbe J.
 Allergy 2008 July;63(7):793-796.

Unproven techniques in allergy diagnosis.  
 Wuthrich B.
 J Investig Allergol Clin Immunol 2005;15(2):2-90