Posts Tagged ‘immunotherapy’

Treating hay fever with grass allergy tablet

Wednesday, March 10th, 2010

The grass pollen hay fever season is fast approaching and those of you prescribed oral immunotherapy should have now commenced treatment at least 2 months before the summer season kicks off in May. For the rest of us, make sure you start taking antihistamine medication at least for a week before those innocent looking lawns and fields start their unrelenting attack on our upper airways. 

Specific grass desensitization to Timothy grass pollen as a treatment for allergy and hay fever has been available for the last 3 years. This sublingual (SLIT) tablet contains a Timothy grass pollen extract which dissolves away under the tongue where it is absorbed promoting immune tolerance to grass pollen when taken over a 3 year period.  Although expensive at over £2 per day, Grazax is an additional option for those severe hay fever  sufferers (with allergic rhinoconjunctivitis) not responding to conventional antihistamine medication and nasal steroid sprays. It can be prescribed on the NHS but many health authorities deem it too expensive for the 30% improvement in hay fever symptoms and reduced medication requirements documented in clinical studies. Many desperate hay fever sufferers have therefore turned to private prescriptions of this disease modifying hay fever tablet.

Reference: Durham SR et al. Long-term clinical efficacy in grass pollen-induced rhinoconjunctivitis after treatment with SQ-standardized grass allergy immunotherapy tablet. Journal Allergy and Clinical Immunology 2010;125:131-38

Peanuts allergy cure is here!

Saturday, October 17th, 2009

In a recent peanut allergy study at Addenbrookes Hospital in Cambridge, traces of peanut flour were used to desensitise 18 highly peanut allergic children. At the end of the study conducted in a controlled hospital environment, they were able to consume 12 peanuts each without any allergic reaction. The study involved eating minute trace amounts of peanut flour mixed with food or drinks on a daily basis to slowly induce peanut tolerance.  Then at regular 2 weekly intervals the peanut flour dose was doubled so that by the 10th hospital visit, they each ate 5-6 peanuts each without reacting on allergy testing. But to maintain thispeanut tolerance they will have to continue eating peanuts regularly on a daily basis, otherwise they may lose this tolerance and their peanut allergy recur.

WARNING: This was a highly controlled study in hospital and peanut allergic children should not be given peanut flour unsupervised!

http://news.bbc.co.uk/2/hi/health/7899383.stm