Skin Allergy

Autoimmune Progesterone Dermatitis

Autoimmune Progesterone Dermatitis is a rare condition related to a hypersensitivity to endogenous overproduction or sensitivity to progesterone the sex hormone in fertile (ovulating) and pregnant women. Those affected develop dermatitis during the luteal phase of their menstrual cycle (7 days before the period commences). The skin lesions can include eczema, folliculitis, hives, Urticaria, small [...]

By | 2016-07-01T14:35:30+00:00 July 1st, 2016|Skin Allergy|0 Comments

Improving the barrier effect of the skin.

Allergic eczema is a genetically predisposed disease (atopy). The atopic skin is a poor barrier to the outside environment, lacking an essential “protective glue” called Filaggrin. Casual contact with traces of foods and aero allergens from handling the infant, then leads to allergen sensitisation, followed by increased natural colonisation with Staphylococcus aureus skin bacteria which [...]

By | 2015-03-13T07:49:54+00:00 March 13th, 2015|Skin Allergy|0 Comments

Confirming Penicillin Allergy

About 15% of the population have a suspected Penicillin allergy usually diagnosed in childhood with a rash and this affects antibiotic prescribing all their life. Recent research has shown that only 3% of those with a suspected Penicillin allergy in fact are allergic on challenge testing. The major problem is that skin prick tests, intradermal tests [...]

By | 2014-09-30T09:50:54+00:00 September 30th, 2014|Skin Allergy|0 Comments

UK nickel coin alert!

New 5 pence and 10 pence coins are being struck at the Royal Mint in the UK.  These cheaper-to-produce coins contain nickel-plated steel, which unlike the older cupro-nickel coins, release up to 4 times more nickel on exposure and raise the risk of increased nickel sensitisation leading to contact dermatitis and eczema. An international study [...]

By | 2013-06-16T19:37:31+00:00 June 16th, 2013|Skin Allergy|0 Comments

Using progesterone contraceptives to treat angioedema

Isolated Angioedema is quite common in middle aged post-menopausal women and initially presents with facial swelling (eyelid, lip and tongue) and then may progress to affect other soft tissues in the throat, armpits and genital area. Tongue and laryngeal angioedema are potentially life-threatening . Many cases are not associated with urticaria or hives and on [...]

By | 2013-04-17T09:45:35+00:00 April 17th, 2013|Skin Allergy|0 Comments

Omalizumab treatment for Chronic Urticaria

Clinical trials are underway to assess the effect of Omalizumab (Xolair) in treating Chronic Spontaneous Urticaria otherwise known as Chronic Idiopathic Urticaria. Omalizumab is a recombinant human monoclonal antibody that binds to IgE preventing it from attaching to the surface of airway mast cells and basophils and currently licenced for use in treating allergic asthma.  [...]

By | 2016-11-21T22:14:11+00:00 November 17th, 2012|Skin Allergy|1 Comment

Fillagrin glue to keep skin intact

Mounting evidence shows that children with eczema do not produce enough essential Fillagrin “glue” that binds the skin Corneocyte cells together in the Stratum Corneum and so prevent irritant chemicals and environmental allergens from penetrating the superficial barrier layers of their skin.  Chemical irritants and protein allergens must break through the top layer of the skin [...]

By | 2013-01-09T12:43:42+00:00 September 1st, 2012|Skin Allergy|0 Comments

Childhood urticaria

Urticaria is a common condition in both adults and also children. The exact cause often remains unclear and antihistamines remain the mainstay of current treatment in most cases. Acute spontaneous urticaria is more common in children, being of short duration (less than 6 weeks) and usually caused by an underlying viral infection and not due [...]

By | 2012-08-24T18:38:02+00:00 August 24th, 2012|Skin Allergy|0 Comments

Rupatadine anti-histamine

Rupatadine is a new non-sedating antihistamine medication used in allergy management of conditions such as allergic rhinitis and chronic urticaria. As well as primarily blocking the Histamine receptors on cells, Rupatadine has a dual effect of also blocking the action of Platelet Activating Factor (PAF). PAF is one of the most potent allergy provoking mediatoirs released [...]

By | 2012-08-08T10:57:05+00:00 August 8th, 2012|Airway Allergy, Skin Allergy|0 Comments