A recent international study has highlighted this condition Food Protein-Induced Enterocolitis Syndrome (or FPIES) related to a delayed allergic hypersensitivity to food that results in infants developing severe colic, feeding difficulties, vomiting and diarrhoea all occurring within 4 hours of feeding. Of the 180 different foods investigated, cow’s milk, soy, rice and oats were most often implicated. Of those affected, 65% reacted to one food (most commonly milk) 26% reacted to 2 foods and 9% reacted to 3 different foods. 40% of Milk FPIES went on to develop IgE mediated milk allergy as well. But thankfully most FPIES will resolve by 5 years of age.

Jean Christoph Caubet et al . Journal Allergy and Clinical Immunology 2014 134; 382-389